Extravasation Injuries: Current Medical and Surgical Treatment

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Extravasation is a devastating complication of intravenous therapy that develops when a drug infiltrates the interstitial tissue surrounding the vein. Due to the uncertain and possibly dramatic outcome, early recognition and adequate treatment with the aid of a standardized protocol are needed.


A pubmed literature search was conducted and all relevant articles were reviewed for the development of an extravasation treatment protocol.


An overview of current treatment guidelines and clinical experience is provided. The extravasation treatment protocol was implied during 1 year in this university hospital with satisfactory outcome.


Treatment starts with prevention. In case of an established extravasation injury, early recognition, assessment of severity, and treatment with medical and/ or surgical therapies are recommended.

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