The analysis of associated circumstances to macular edema will help the clinician to select one among the different therapeutic options of macular edema (ME). The duration of ME, the efficacy of previous treatments, the ability of the patient to be examined regularly will influence this choice. The different options are grid laser, antiVEGF agents, steroids. Associated risk factors like severe glaucoma or lens status also need to be considered. The control of systemic conditions remain a key issue. The strategy can change during the follow-up according to the efficacy and the recurrences observed with the treatments.