To characterise the cellular mechanisms of fluid flow in the retina in view of its clinical implications.Background:
Retinal fluid homeostasis is effected by a whole host of mechanisms that reside both in the retinal pigement epithelium, in the choroid and in the retina. In a physiological state there is a constant flow of fluid out of the intraretinal and subretinal space into the choroid, of which about 70% is effected via active transport mechanisms within in the retinal pigment epithelium.In case these Results:
This presentation will summarise the latest data on how fluid homeostasis is maintained within the retina and how these mechanisms underly the evolving phramacological treatment modalities for exudative maculopathies.Conclusion:
The understanding of the cellular mechanisms that govern retinal fluid flow is crucial to the cinical application of medical treatments against exudative maculopathies.