"No-touch" DMEK: Learning curve and outcomes

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Descemet Membrane Endothelial Keratoplasty (DMEK), as described by Gerrit Melles in 2002, is currently the most targeted technique of endothelial replacement, as only Descemet membrane and the endothelial monolayer are transplanted. Therefore, the postoperative anatomy of the cornea is not altered as in earlier techniques (DLEK, DSAEK) and visual rehabilitation is fast and frequently complete. In the present lecture, surgical videos of graft preparation and DMEK surgery with the standardized “no touch” techniques as described by Melles will be presented along with clinical outcomes with regards to corrected visual acuity, refraction, endothelial cell density, complications and secondary procedures.

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