Filamentary keratitis epidemiology

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To analyze concomitant pathology contributing to filamentary keratitis.


We examined 38 patients (76 eyes) with filamentary keratitis. All of them were consulted by co-specialists (internist, endocrinologist, reumatologist) with the object to reveal concomitant diseases. The treatment regimen included keratoprotectors, artificial tears, 0,1% dexamethasone, 0,05% cyclosporine. Besides, in case of decompensated concomitant disease patients were treated by appropriate specialist. Among investigative methods were: biomicroscopy, Shirmer test – 1, TBUT-test. Follow-up period was 3-5 months.


Among concomitant pathology we revealed: § Thyroid gland disfunction (hypothireosis) – 34,2 % § Rheumatoid arthritis – 21,1 % § Sjögren's Syndrome – 2,6 % § Diabetes mellitus of 2nd type – 7,9 % § Combination of rheumatoid arthritis and thyroid gland dysfunction (nodes against a background of euthyreosis) – 10,5 % § Combination of diabetes mellitus of 2nd type and thyroid gland dysfunction – 13,2 % § Neither endocrine nor rheumatoid diseases revealed – 10,5 %. Among them 1 patient after previous PRK. Shirmer test – 1 results were variable and no appropriateness with treatment regimen was found. TBUT-test data before treatment were low (6-9 sec.) with an increase up to 9-11 sec. after the treatment.


89,5 % of patients had endocrine pathology or rheumatoid diseases or their combination. With this in view, we may consider filamentary keratitis not as a form of severe dry eye syndrome, but as a separate dystrophic corneal disorder with dry eye as its symptom.

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