Definition of a normative basis for peripapillary nerve fibers thickness in childhood with sd-oct

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Abstract

Purpose

Since its inception, optical coherence tomography (OCT) has radically changed our way to practice ophthalmology. Yet, the analysis of databases of various machines has no value for patients under 18 years old. In this work we define a normative basis of the thickness of peripapillary nerve fibers in children with SD-OCT.

Methods

We randomly selected 99 children (192 eyes) aged from 2 to 17 years. They were found to be healthy subjects with no history of eye disease and normal visual acuity. A study of the optic nerve head was conducted on Cirrus HD OCT. Two scans were performed in both eye to judge the good reproducibility of the measurement. We divided the population into three age groups (Group 1: 3-7 years / Group 2: 7-12 / Group 3: 12-18 years) before setting the average thickness of each quadrant.

Results

Group 1 included 10 patients (19 eyes). The results reflected an overall thickness of 100μm +/- 8 to the following distribution: temp: 77μm +/-8 / Upper: 130 μm +/-20 / nasal: 66μm +/ -10 / lower: 131μm +/-12. Group 2 included 39 patients (74 eyes). The results reflected an overall thickness of 99μm +/- 8 to the following distribution: temp: 72μm +/-9 / Upper: 126 μm + / -16 / nasal: 70μm +/-13 / lower: 128μm +/-16. Group 3 included 50 patients (99 eyes). The results reflected an overall thickness of 97μm +/- 11 for the following distribution: temp: 63 μm +/-14 / Upper: 125μm +/-16 / nasal: 72μm +/-15 / lower: 128 +/-19.

Conclusion

The definition of a normative database in children is essential on OCT because it's integrated into the daily practice of the ophthalmologist. We define RFNL in children under 18 years old and find a very slight change over time, mainly in the temporal quadrant.

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