Neuromyelitis optica (devic‘s disease): The use of the spectral domain optical coherence tomography (OCT) in the follow up of the disease

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To report a case of neuromyelitis optica (Devic’s disease) which followed up with the use of optical coherence tomography (spectral domain OCT)


A 24 year old female patient presented with vision deterioration due to acute onset of unilateral optic neuritis in her left eye (OS)She was referred to the neurologic department of our hospital for further assessment and the diagnosis of Devic’s disease was set by the presence of anti – NMO – IgG antibodies. Patient’s follow – up included visual acuity measurements, visual fields testing and electrophysiological evaluation with pattern visual evoked potentials (PVEP) according to ISCEV standards. Peripapillary RNFL thickness was assessed by the spectral domain OCT


Visual acuity was measured at 1.0 at her right eye and 0.4 at her left eye. Visual field of her left eye showed a characteristic scotoma due to optic neuritis. The latency of the P100 was delayed demonstrating dysfunction of the optic nerve pathway. Thinning of the RNFL layer was documented in her left eye at OCT imaging. During follow up of the patient there was no further deterioration of the RNFL thickness despite recurrence of the optic neuritis three times


OCT is a valuable and sensitive tool in evaluating peripapillary RNFL in patients with neuromyelitis optica (νóσ[omicron][sigmaf] Devic).

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