Progression of visual field in patients with primary open-angle glaucoma (2): Level of progression

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To compare the visual field rate (VF) of progression of non evolutive and evolutive patients with treated ocular hypertension (OHT) or primary-open angle glaucoma (POAG).


From a multicentric database, 441 eyes of 228 patients with treated OHT or POAG followed up at least 6 years with Humphrey 24.2 Sita-Standard VF exam at least twice a year were identified and classified in 5 groups: 104 OHT, 205 early glaucoma (MD>-6dB), 45 moderate glaucoma (MD-6 to -12dB), 41 advanced glaucoma (MD-12 to -18dB) and 46 severe glaucoma (MD<-18dB). With final datas, patients were classified in 2 sub groups: “evolutive” or “stable” patients if worsening or not to upper grade. Rate of progression during follow-up period was calculated using the trend analysis of the Guided Progression Analysis software.


The mean follow-up was 8.4 years. We found respectively for “stable” and “evolutive” sub-groups, following rates of progression : MD =-0.01 and -0.13dB/year (-0.03& -0.41%VFI/year) in eyes with OHT, -0.07& -0.80dB/year (-0.23 & -2.39%VFI/year) in early glaucoma group, -0.02& -0,91 dB/year (-0.46 & -3.04%VFI/year) in moderate glaucoma, -0.21 & -0.82dB/year (-1.13 & -3.57%VFI/year) in advanced glaucoma.


In early to advanced stages of glaucoma, “stable” patients showed a low rate of progression, compared to “evolutive” subgroup with a common rate around -0.80dB/year. These values could represent a landmark of evolution in glaucoma.

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