Evidence for oxygen use in preterm infants

    loading  Checking for direct PDF access through Ovid

Abstract

Aim:

To review the evidence for optimal oxygen use in preterm infants.

Results:

Clinicians have embraced lower saturation targets to minimize retinopathy of prematurity (ROP). Large randomized trials now have shown that while such targets reduce ROP, neonatal mortality is increased significantly.

Conclusions:

Preterm infants should be resuscitated with blended oxygen (30–90%) targeted to avoid hyperoxia. Later, saturation management remains uncertain. Until ongoing trials and follow-up are complete, it is prudent to avoid saturation of 85–89%.

Related Topics

    loading  Loading Related Articles