Multimodular Optogenetics
Importance of mitochondrial adaptations to exercise training and performance
1:1 Novel Principles of renal K+ excretion
1:2 Regulation of NCC activity in renal K+ homeostatic response
1:3 The nature and regulation of flow-induced renal K+ secretion
1:4 Is preeclampsia a variant of Liddles syndrome with enhanced activity of the epithelial sodium channel in the kidneys?
1:5 A novel mutation affecting the arginine-137 residue of AVPR2 in male dizygous twins leads to congenital nephrogenic diabetes insipidus and attenuated urine exosome aquaporin-2
2:1 Novel signal pathways in inflammation - MKP-1 and TRPA1 in the focus
2:2 The role of TRPA1 in pain and inflammation
2:3 Inflammation as a therapeutic target in stroke
2:4 Impaired Cyclooxygenase-2 Expression Leads to Aggravated Renal Fibrosis in Response to Unilateral Ureteral Obstruction in Mice
2:5 Deficiency of Microsomal Prostaglandin E Synthase-1 Exacerbates Renal Fibrosis and Inflammation in Mice with Unilateral Ureteral Obstruction
W1 Mechanogenetic Control of Endothelial Function
W3 Living Photonics (LiPhos) Single Cell Analysis - Label Free Detection Methods
3:1 A translational animal model of perceived pain magnitude using novel cortically implanted neural interfaces
3:2 Visceral pain: basic, translational and clinical perspectives
3:3 Intrinsic cold and heat sensitivity of the nocisensor TRPA1
3:4 Aerobic exercise reduces pallesthesia and myofascial pain in man
3:5 Changes of nervous conduction in transgenic mice with a changed metabolism of nerve fibres
4:1 Lymphatic pump and valve dysfunction in genetic models of lymphatic disease
4:2 A new role of the interstitium and lymphatics in the development of hypertension
4:3 Ion channels and lymphatic vessel function
4:4 A functional role for pacemaking HCN channels in lymphatics?
Physiology of ejaculation
The senescent regenerated endothelium: the weak ling…
5:1 New for Old - Addressing bladder and bowel function with tissue engineering and regenerative medicine
5:2 Scaffold-free tissue engineering under microgravity conditions
5:3 Regenerating Organs and Tissues: from Bench to Bedside
5:4 High salt diet results in a hypertonic skin microenvironment
6:1 Carbonic anhydrase VII: Neuronal pH regulatory protein with morphogenic functions
6:2 A passive pathway for venting metabolic acid from hypoxic tumour regions
6:3 Sensing and transport of HCO3- in the vascular wall
6:4 Role of potassium channels in the regulation of proton (H+/K+ ATPase) pump activity in pancreatic duct epithelial cells
6:5 Extracellular Acidosis Inhibits Lymphatic Vessel Contractility
7:1 Combination of genetic and epigenetic sequencing approaches to unravel the altered gene regulatory structure in cancer
7:2 The use of genetic variation to predict age-related diseases as cardiovascular disease and Dementia
7:3 The Pharmacogenetics of Metformin
7:4 “Mutations in the human SLC34A2 gene - characterization and effect on phosphate transport in Pulmonary Alveolar Microlithiasis”
7:5 Treatment with metformin improves endothelial function in aortic tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic conditions.
8:1 Kv7.4 and Kv7.5: guardians of smooth muscle excitability.
8:2 Functional roles of Kv7 channels in the hippocampal-entorhinal memory system
8:3 Kv7.1 surface expression; a regulatory mechanism for insulin secretion
8:4 Altered stiffness in coronary arteries and effect of pirfenidone on endothelium-dependent vasodilatation in type 2 diabetic (db/db) mice
8:5 Inhibition of KV7 channels protects against myocardial ischemia and reperfusion injury
9:1 Central nervous system control of hibernation reveals opportunities for human hibernation
9:2 Are you dead, just because you are cold?
9:3 Power napping extreme - hibernation in primates?
9:4 Regulation of hemoglobin oxygen affinity in hibernating animals
9:5 The physiology of chill susceptibility in insects
10:1 Physiology of hibernation as an angle to understand heart failure
10:2 The Pathophysiology of the broken heart
10:3 Cardiac serotonin receptors and natriuretic peptide receptors as potential targets for heart failure therapy
10:4 Circadian Rhythms in Cardiac Electrophysiology
10:5 BIN1 regulates t-tubule growth during development and disease
11:1 Oxygen uptake dynamics during exercise
11:2 Maximal heart rate and cardiovascular capacity in humans
11:3 Blood flow restricted and traditional resistance training performed to fatigue produce equal muscle hypertrophy
11:4 Skeletal muscle dysfunction in the db/db mice model of type 2 diabetes
11:5 Regional differences in signaling pathways activity and gene expression levels in rat gastrocnemius muscle after a series of intense contractions
Purinergic signaling in the lung: from bench to bedside and back again
The nightlife of astrocytes
12:1 Defects of plasma membrane proteins: The first step to hyperaldosteronism?
12:2 Primary aldosteronism - from genetic abnormalities to pathophysiological models
12:3 Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension
12:4 Angiotensin II AT1-receptor blockade using Losartan does not impair renal oxygenation following hemorrhage
12:5 Deficiency of the T-type calcium channel Cav 3.1 attenuates plasma aldosterone and cardiac hypertrophy despite similar AngII-induced hypertension
13:1 The role of the mucosa in normal and abnormal bladder function
13:2 MicroRNAs in bladder outlet obstruction: relationship to matrix remodelling and growth.
13:3 Inhibitory effects of urothelium-related factors, including PGD2, in guinea-pig urinary bladder
13:4 Role of SK3 channels in erectile function in mice
13:5 Interstitial Cajal-like cells in the female reproductive tract
14:1 Capillary flow patterns and brain oxygenation
14:2 Regulation of cerebral blood flow by capillary pericytes, in health and disease.
14:3 Measuring microscopic flow patterns and brain oxygenation
14:4 The α-2 Isoform of Na,K-ATPase Modulates Vascular Tone via Activation of Src -kinase (Src) Signaling Pathway: a Lesson from Mouse Model for Familial Hemiplegic Migraine Type 2 (FHM2).
14:5 Changes in vasoreactivity following middle cerebral artery occlusion
15:1 ATP-dependent Lipid Pumps: Linking Lipid Transport to Cell Function and Disease
15:2 Lipid pumps and ion pumps: how different are they?
15:3 The role of lipid flippases in bile formation
15:4 Biochemical characterization of P4-ATPase mutations associated with Intrahepatic Cholestatic Disease
16:1 Using molecular genetics to short the circuitry of memory
16:2 The Arc of synaptic memory
16:3 I can make you move! - The remote control of nerve cell transplants
16:4 Mapping the dualistic profile of an allosteric AMPA receptor modulator -studies on recombinant receptors, mouse hippocampal synapses and crystal structures
17:1 Targeting Protein Disulfide Isomerase for Antithrombotic Therapy
17:2 Novel oral anticoagulants and the clinical pharmacological/therapeutic aspect of therapeutic drug monitoring
17:3 Aspirin in coronary artery disease - Investigation of the effect Potential causes of reduced antiplatelet effect
17:4 Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus
17:5 Right Ventriculo-Arterial Interaction in Health and Disease as Assessed by Wave Intensity Analysis
P1 KV7 channel impairment occurs before the onset of hypertension in rats on a high fat and fructose diet.
P2 Hemodynamic effects of intracardially infused clusterin in the anesthetized rat
P3 Initial investigations into the effect of clusterin on cardiac ischemia—reperfusion injury in vivo
P4 Action of somatostatin and analogues on human lymphatic vessels
P5 Involvement of hydrogen sulfide in perivascular and hypoxia-induced inhibition of endothelin contraction in porcine retinal arterioles
P6 The Role of Adenosine Receptors in Hypoxic Vasodilatation and Cardioprotection
P7 Placental vessels from type—1 diabetics and the surrounding tissue
P8 In vitro study of the vasodilatory effect of pomegranate flower—polyphenols on the aorta ring of Sprague-Dawley rats
P9 Pro-contractile action of the ouabain-sensitive Na,K-ATPase in the vascular wall is associated with Src -kinase activation.
P10 Validation of Near Infrared Fluorescence (NIRF) Imaging of lymphatic vessels in humans
P11 The cardiovascular pharmacology of the venom of the Papuan black snake Pseudechis papuanus
P12 Pharmacological analysis of endothelial influences in basilar artery of C57BL/6 mice
P13 Perivascular tissue affects regulation of coronary artery tone
P14 Effects of an opener of small and intermediate calcium-activated K channels NS309 on cardiac rhythm and erectile function in rats
P15 Lamin A/C disruption in white blood cells augments leukocyte extravasation and atherosclerosis development in Ldlr -KO mice
P16 Late onset vascular dysfunction in the R6/1 model of Huntington's disease
P17 TMEM16A is upregulated, but does not translate into increased contractility of mesenteric arteries in streptozotocin model of type 1 diabetes
P18 Deficiency of thyroid hormones in early development provokes alterations in nervous control of cardiovascular system
P19 Endothelial dysfunction in small renal arteries as a mechanism of diabetic hyperfiltration
P20 The role of NA and ATP signaling in perivascular nerves in vivo
P21 Nicotine exacerbates diabetes-associated cardiac dysfunction
P22 Tyrosine kinase inhibitor-induced hypertension in patients diagnosed with renal cell carcinoma is associated with decreased urinary excretion of NO metabolites
P23 Cancer and melancholia: two “scourge” diseases of the modern world were historically connected
P24 Common Effects on Follicular Thyroid Cancer Cells Exerted by Simulated Microgravity
P25 Nitrite-dependent modification of mitochondria protects against oxidative damage in turtles
P26 C57BL/6J mice are resistant to cardiorenal syndrome during high-salt and Angiotensin II treatment compared to Balb/c because of higher oxidative stress.
P27 Effects of reduced tetanic calcium concentration on the curvature of the force-velocity relationship in isolated rat soleus muscles.
P28 Aggregation of isolated hemoglobins from the turtle, Trachemys scripta .
P29 Comparison of circulating hydrogen sulfide and nitric oxide metabolites and their potential roles in brown bear hibernation
P30 Pump those ions or you'll wake up dead: Key differences in how chilling affects tropica and temperate Drosophila species
P31 Scanning mutagenesis of transmembrane segments M5 and M6 of the mammalian flippase ATP8A2 - evidence for a classic transport pathway?
P32 TRP channels function is tightly regulated during early embryo development
P33 Is the potassium channel ROMK suppressed in patients with proteinuria?
P34 The in vitro NCX1 interactome
P35 Modulation of GABAA receptor-mediated synaptic and tonic currents in the rat hippocampus by GLP-1, exendin-4 and diazepam
P36 Insulin modulates GABAA receptor-mediated neuronal inhibition in rat hippocampus and amygdala
P37 ComparingATP1A3 mutations causing neurological diseases
P38 The mRNA expression of GABA-A, GABA-B receptor subunits and chloride transporters in peripheral blood mononuclear cells is influenced by gender, pregnancy and depression.
P39 More severe structural alterations in the cirrhosis phase of the Abnormal Savda syndrome-based hepatocarcinoma
P40 Effect of Abnormal Savda Munziq on Hepatocarcinoma rat model
P41 Synergistic Attenuation of Abnormal Savda Munziq Combination with 5-Fluorouracil on Transplantated cervical cancer (U27) Tumor
P42 Dietary intake of coriander and spinach increases the risk of intensifying the inflammation in the rat models of DNCB—induced ulcerative colitis
P43 Healing effect of Xipayi Kui Jie-an on the pathology and ultrastructure of colon tissues in model rats of Abnormal Sapra with ulcerative colitis
P44 Effects of Xipayi Kui Jie-an on the serum metabolites of the model rats of Abnormal Sapra with ulcerative colitis
P45 The diversity of Intestinal microflora in differentiation of persons with different hilits of Traditional Uighur Medicine
P46 Sequential Glycan Profiling at Single Cell Level with the Microfluidic Lab-in-a-Trench Platform
P47 Utilising the Microfluidic Lab-in-a-Trench Platform to Enable Single Cell Level Drug Screening of Hepatocytes