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Preface
The doctrine of the two depressions in historical perspective
Resurrecting melancholia
Defining melancholia
The facets of melancholia
The incidence and prevalence of manic-melancholic syndromes in North West Wales
A mixed state core for melancholia
Melancholia agitata and mixed depression
Atypical depression
Melancholia and atypical depression in the Zurich study
Epidemiology of subtypes of depression
Pathophysiology of hypercortisolism in depression
Sleep and circadian rhythms in mood disorders
Does dopamine dysfunction drive depression?
Treatment response in melancholia
Electroconvulsive therapy in melancholia
Melancholia