Arthritis as a presenting feature of non-Hodgkin's lymphoma

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Leukaemia can present with joint swelling in the absence of abnormal haematological findings.Arthritis as a presenting sign of lymphoma, however, is extremely rare. Three children with non-Hodgkin's lymphoma who had joint swelling at the onset of their disease are reported. Two cases showed histological features of anaplastic large cell lymphoma (Ki-1/CD30 positive), and one of angioimmunoblastic T cell lymphoma. In all patients the unusual presentation delayed correct diagnosis.(Arch Dis Child 1998;78:367-370)

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