P2 The growth characteristics of children and adolescents with bronchial asthma

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There is a discussion about the deceleration of linear growth in children with bronchial asthma (BA). However, opinions about the impact of BA on children’s growth are ambiguous.

Materials and methods

The study involved 887 children with varying severity of asthma at the age of 5–17 years, the average age of 10,9±3,4 years, of which 655 boys. Assessment of growth was performed in patients according to the Z-score (WHO).


Reduced growth is found in 11.5% of BA patients (102/887): 10.6% of boys (70/655) and 13.8% of girls (32/232), patients with asthma with a higher growth amounted to 25, 6% (227/887): boys 26.9% (176/655), girls 22% (51/232). Harmonious development occurred in 34.8% (309/887) of patients, among boys at 34.4% (225/655), including girls from 36.2% (84/232). Worsening of asthma is accompanied by an increase in the proportion of children with low growth: BA intermittent – 5.0% (5/101), BA mild persistent – 10.5% (47/447), BA moderate persistent – 12.3% (34/277), BA severe persistent – 25.8 (16/62) and a decrease in the proportion of children with elevated growth: BA intermittent – 36.6% (37/101), BA mild persistent – 24.6% (110/447), BA moderate persistent – 24.5% (68/277), BA severe persistent – 17.7% (11/62). The differences are statistically significant, χ2=32.8, p<0.0001. With increasing severity of asthma was also observed decrease in the proportion of children with harmonious development – BA intermittent – 39.6% (40/101), BA mild persistent – 36,7% (164/447), BA moderate persistent – 32.1% (89/277), BA severe persistent – 25.8 (16/62), χ2=4.1, χ=0.04.


The results are in agreement with studies showing the deceleration of linear growth in some children with asthma. This requires studying of the mechanisms of the above phenomenon.

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