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Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection
Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury
Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal
Membrane cholesterol content plays a key role in the neurotoxicity of β-amyloid: implications for Alzheimer's disease
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
Candidate gene study of FOXO1 , FOXO4 , and FOXO6 reveals no association with human longevity in Germans
Fat maintenance is a predictor of the murine lifespan response to dietary restriction
Endoplasmic reticulum stress in wake-active neurons progresses with aging
Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women
The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro
Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
Loss of intestinal nuclei and intestinal integrity in aging C. elegans
The −980C /G polymorphism in APH-1A promoter confers risk of Alzheimer's disease
Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant?
The dynamin-related protein DRP-1 and the insulin signaling pathway cooperate to modulate Caenorhabditis elegans longevity
Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan
Research Studentships 2011/12
Biogerontology Faculty Position, University of Michigan