logo
Hot topics in epigenetic mechanisms of aging: 2011
Pharmacological maintenance of protein homeostasis could postpone age-related disease
New genes that extend Caenorhabditis elegans ’ lifespan in response to reproductive signals
Myosin light chain 3f attenuates age-induced decline in contractile velocity in MHC type II single muscle fibers
Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity
Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis
The CETP I405V polymorphism is associated with an increased risk of Alzheimer’s disease
Characterization of cellular senescence mechanisms in human corneal endothelial cells
Adult neurogenesis in the short-lived teleost Nothobranchius furzeri : localization of neurogenic niches, molecular characterization and effects of aging
Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri – a new vertebrate model for age research
CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength
Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice
Age-dependent skewing of X chromosome inactivation appears delayed in centenarians’ offspring. Is there a role for allelic imbalance in Healthy Aging and Longevity?
Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging
Identification of age-specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?
Age-dependent reduction of the PI3K regulatory subunit p85α suppresses pancreatic acinar cell proliferation
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling
Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting d-serine-dependent NMDA receptor activation
A senescent cell bystander effect: senescence-induced senescence
Linkage of cardiac gene expression profiles and ETS2 with lifespan variability in rats
A neuroprotective role for the DNA damage checkpoint in tauopathy
Replication factor C1, the large subunit of replication factor C, is proteolytically truncated in Hutchinson–Gilford progeria syndrome
Monitoring of cellular senescence by DNA-methylation at specific CpG sites