Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease
Glucocorticoids suppress selected components of the senescence-associated secretory phenotype
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death
Contribution of serine racemase/d-serine pathway to neuronal apoptosis
Molecular phenotyping of aging in single yeast cells using a novel microfluidic device
Genome-wide miRNA signatures of human longevity
The heat shock transcription factor Hsf1 is downregulated in DNA damage–associated senescence, contributing to the maintenance of senescence phenotype
Changes in neuronal DNA content variation in the human brain during aging
Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster
Caloric restriction may reverse age-related autonomic decline in humans
Altered regulation of CXCR4 expression during aging contributes to increased CXCL12-dependent chemotactic migration of CD4+ T cells
An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan
Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress
Rapamycin slows aging in mice
Distinct effects of inflammation on gliosis, osmohomeostasis, and vascular integrity during amyloid beta-induced retinal degeneration
Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs
Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging
The oxidative DNA lesions 8,5′-cyclopurines accumulate with aging in a tissue-specific manner
Host cell factor 1 inhibits SKN-1 to modulate oxidative stress responses in Caenorhabditis elegans
The number of p16INK4a positive cells in human skin reflects biological age
The NIA Interventions Testing Program Announces the 2012 Solicitation of Proposals