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Hutchinson–Gilford progeria syndrome through the lens of transcription
Age-related degeneration of the egg-laying system promotes matricidal hatching in Caenorhabditis elegans
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast
Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension
Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica : underlying mechanisms for slow aging
Loss of the Birt–Hogg–Dubé gene product folliculin induces longevity in a hypoxia-inducible factor–dependent manner
Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X
Tracking and fixed ranking of leukocyte telomere length across the adult life course
Implications of time-series gene expression profiles of replicative senescence
Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
Reducing signs of aging and increasing lifespan by drug synergy
Expression of catalytically active matrix metalloproteinase-1 in dermal fibroblasts induces collagen fragmentation and functional alterations that resemble aged human skin
A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys
Pro-inflammatory capacity of classically activated monocytes relates positively to muscle mass and strength
A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family
Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1
Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice
Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive
Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast
Mitochondrial mutations and aging: random drift is insufficient to explain the accumulation of mitochondrial deletion mutants in short-lived animals
The NIA Interventions Testing Program Announces the 2013 Solicitation of Proposals