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Reduced naïve CD8+ T-cell priming efficacy in elderly adults
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
Predicting all-cause mortality from basic physiology in the Framingham Heart Study
Reduction of fibroblast size/mechanical force down-regulates TGF-β type II receptor: implications for human skin aging
Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment
Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial
Type 5 adenylyl cyclase disruption leads to enhanced exercise performance
Homeostatic dysregulation proceeds in parallel in multiple physiological systems
CALHM1 and its polymorphism P86L differentially control Ca2+ homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β
CBX7 and miR-9 are part of an autoregulatory loop controlling p16INK 4a
Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities
Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans
Integration of ‘omics’ data in aging research: from biomarkers to systems biology
Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice
The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging
Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via KC a1.1 upregulation
The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?
Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna Dhe mice
Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice
Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response
Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood–brain barrier dysregulation in a mouse model of telomere shortening
Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase
Demographic and clinical variables affecting mid- to late-life trajectories of plasma ceramide and dihydroceramide species
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
Circulating microRNA signature of genotype-by-age interactions in the long-lived Ames dwarf mouse
β-Guanidinopropionic acid extends the lifespan of Drosophila melanogaster via an AMP-activated protein kinase-dependent increase in autophagy
DNA methylation and healthy human aging
The cerebral cavernous malformation 3 gene is necessary for senescence induction
Aging and radiation: bad companions
Aberrant post-translational modifications compromise human myosin motor function in old age
Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis
Daumone fed late in life improves survival and reduces hepatic inflammation and fibrosis in mice
Modulated expression of human peripheral blood microRNAs from infancy to adulthood and its role in aging
Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals
Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence
Cellular senescence and aging: the role of B-MYB