Top-Down Fabrication of Polyelectrolyte-Thermoplastic Hybrid Microparticles for Unidirectional Drug Delivery to Single Cells

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Abstract

This manuscript describes an inexpensive and versatile top-down method to produce microparticles

that integrate both thermoplastics and polyelectrolytes with a unique dot-on-pad structure. These particles may allow in vivo unidirectional drug delivery to single cells.

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