Tuning Reaction and Diffusion Mediated Degradation of Enzyme-Sensitive Hydrogels

    loading  Checking for direct PDF access through Ovid


Enzyme-sensitive hydrogels are promising for cell encapsulation and tissue engineering, but result in complex spatiotemporal degradation behavior that is characteristic of reaction-diffusion mechanisms. An experimental and theoretical approach is presented to identify dimensionless quantities that serve as a design tool for engineering enzyme-sensitive hydrogels with controlled degradation patterns by tuning the initial hydrogel properties and enzyme kinetics.

    loading  Loading Related Articles