Determinants of adherence to non-occupational post HIV exposure prophylaxis


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Abstract

We conducted a study on 140 patients who sought advice at hospital after a non-occupational exposure. The full 28-day course of prophylactic antiretroviral therapy was completed by 109 patients. No HIV contamination was observed. Factors associated with suboptimal adherence were African ethnicity [odds ratio (OR) 13.3, 2.02–87.54] and oral sexual intercourse (OR 8.35, 1.66–41.99). Compliance with prophylactic antiretroviral therapy can be increased by addressing social and psychological barriers to adherence.

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