Low Association of HLA-B27 with Reiter's Syndrome in Blacks

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Abstract

The association between ankylosing spondylitis and HLA-B27 has been noted in all races that have thus far been studied; it tends to be strongest in whites and relatively weaker in blacks (1–3). Reiter's syndrome is also strongly associated with HLA-B27 in whites (1), but has not been well studied in blacks (3). Morris and associates (4) have suggested the use of B27 typing in the clinical evaluation of white male patients with suspected Reiter's syndrome and have predicted that the test would be even more helpful in blacks. We report here the results of our study of the diagnostic usefulness

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