To the editor: In “Cholesterol Embolism: Diagnosis Antemortem by Bone Marrow Biopsy,” in the December 1978 issue (1), Pierce and associates state that cholesterol emboli diagnosed by bone marrow biopsy have not been previously reported.
I have seen cholesterol emboli in histologic preparations of aspirated and biopsied marrow on several occasions and have reported it (2). A word of caution is in order. The finding of atheromatous emboli in the bone marrow does not necessarily mean that the patient is suffering from widespread manifestations of this process. It may be an incidental finding of minor clinical significance indicating that the