Clinical Pharmacology. Basic Principles in Therapeutics. Second Edition. Edited by Melmon Kenneth L. Morrelli Howard F. pages. Macmillan Publishing Company, Inc., New York, 1978. Price, $25.00, hardcover; $19.95, softcover.

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New chapters on “Clinical Pharmacokinetics: The Use of Plasma Concentrations of Drugs,” “Psychologic Factors in Drug Administration,” “Pharmacodynamics and Drug Disposition in Pregnant Women, in Neonates, and in Children,” “Dermatologic Disorders,” “Alcohol and Drug Abuse,” “Qualitative Aspects of Therapeutic Decision Making,” and “Economics and Epidemiology of Drug Use.” With 42 contributing authors, the book is organized into units on general principles that apply to all therapeutic decisions, pathophysiologic and pharmacologic considerations, and recognition and evaluation of effects of drug administration. Not a basic text in pharmacology or medicine but intended as a supplement to both. Includes a 35-page subject index.

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