To the editor: We read with interest the paper by Aisner and associates in the January 1979 issue (1), which reports the predictive value of positive nasal cultures for Aspergillus species in the diagnosis of invasive aspergillosis in patients with acute leukemia. We wish to report the successful treatment of a patient based on their data.
A 48-year-old woman with acute nonlymphocytic leukemia in relapse was admitted to the Peter Bent Brigham Hospital for evaluation of fever and a pulmonary infiltrate. The patient had been severely granulocytopenic (neutrophils, < 500/mm3) for 8 weeks before admission. On admission, the temperature was