Histamine II and Anti-Histaminics. Chemistry, Metabolism and Physiological and Pharmacological Actions. Edited by Rocha e Silva Mauricio Rothschild Hanna A., pages. Springer-Verlag, Berlin, Heidelberg, and New York, 1978. Price, $156.40.

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An exhaustive, richly referenced monograph on the pharmacologic actions of histamine (cardiovascular, gastric); histamine release; enzymatic assay; and anti-histaminic structure and function relations, mechanisms of action, and pharmacologic and therapeutic effects. The audience is mainly nonclinical but sections will be excellent fundamental sources for persons needing to review the journal literature basic to clinical therapy.

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