Pheochromocytoma and Vasodepressor Response to Saralasin

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Abstract

To the editor: Although a severe delayed hypertensive crisis has been reported in a patient with a pheochromocytoma after saralasin infusion (1) we have seen a patient with both renovascular hypertension and an extra-adrenal pheochromocytoma who had only a sustained vasodepressor response to saralasin.

A 10-year-old white boy presented with sudden onset of severe headaches and hypertension in February 1976. Blood pressure was 210/130 mm Hg. Fundi were grade II. Heart and lung examination findings were unremarkable except for sinus tachycardia. A 24-h urine contained 7.9 mg of vanillylmandelicacid (normal range, 1 to 10 mg) and 226 mg of catecholamines

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