Aluminum and Dialysis Dementia

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To the editor: The paper by Arieff and colleagues on dialysis dementia in the May issue (1) misquotes one of our papers (2) and draws erroneous conclusions about aluminum toxicity in rats. Arieff and associates decided that our rats died of aspiration pneumonia. This is not correct. It would have been remarkable if those rats given oral A1C13 and A1SO4 solution to drink had inhaled A1(OH)3. Hypostatic pneumonia, not aspiration pneumonia, was found. The histologic appearances of aluminum hydroxide aspiration were not present, nor did we mention aspiration pneumonia as a factor. Similar toxic effects in rats have been found

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