Adrenal Scintiscanning and Aldosteronism

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To the editor: The article “Primary Aldosteronism” by Weinberger and colleagues (1) raised questions on the efficacy and reliability of adrenal scintiscanning procedures. We wish to comment on the cases referenced in that article that were imaged by our group and on our further experience with these procedures.

Four patients were seen at the University of Michigan Medical Center before the radiopharmaceutical was available at Indiana University. Their cases were 16, 44, 46, and 50; the patients were studied during the interval from March to October 1972. All patients received from 1.75 to 2.0 mCi of 131I-19-iodocholesterol (NM-145) intraveneously and

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