Performance of Ergonovine Provocative Testing for Coronary Artery Spasm

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Ergonovine provocative testing for coronary artery spasm involves intravenous infusion of ergonovine maleate (under carefully controlled circumstances) in an attempt to provoke coronary artery spasm during the evaluation of possible variant angina. A classic positive response consists of coronary arterial spasm accompanied by the elevation of at least one ST segment on the scalar electrocardiogram (1, 2). However, spasm shown by angiography can occur without accompanying ST segment elevation, and ST segment elevation may not always be accompanied by coronary artery spasm.


Ergonovine provocative testing appears to be safe in patients who have neither variant angina nor fixed coronary

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