Women with serious mental illness are a population at risk because of their invisibility. A comprehensive and critical literature review documents the issues and gaps in this aspect of the health care environment for women. A conceptual model outlines the current health-related risks for women with serious mental illness. Use of a feminist perspective challenges the underlying assumptions and opens new arenas for research and practice. The speculative, theoretical context thus created encourages and supports the questioning process that is the precursor to change.