Clinical impact of switching conventional enzyme immunoassay with nucleic acid amplification test for suspectedClostridium difficile-associated diarrhea

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The impact of a new Clostridium difficile nucleic acid amplification test (NAAT) on antibiotic utilization in patients with suspected C difficile infection was assessed. This single-center, cross-sectional study of 270 patients demonstrated that the use of NAAT decreased antibiotic expenditure by reducing prolonged empiric days of therapy in these patients.

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