Clinical outcome of dual colistin- and carbapenem-resistantKlebsiella pneumoniaebloodstream infections: A single-center retrospective study of 75 cases in India


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Abstract

Highlights:Outcomes of 75 patients with colistin-resistant Klebsiella pneumoniae bloodstream infections were examined.We observed a high in-hospital mortality rate of 69.3% (52/75 patients).Among the 52 patients who did not survive, 28 patients died within 48 hours of bacteremia.In this study, we retrospectively evaluated clinical outcomes of 75 patients with dual colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections over a 5-year period in a single tertiary care hospital in India. We observed a high in-hospital mortality rate of 69.3%. Our findings indicate the urgent need for new antibiotics to treat these infections.

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