Chlorhexidine gluconate bathing practices and skin concentrations in intensive care unit patients


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Abstract

HighlightsWe performed a real-world evaluation of chlorhexidine gluconate (CHG) skin concentrations in intensive care unit patients and their relationship to different CHG bathing practices.We observed lower skin CHG concentrations among patients when rinsing with water after CHG solution bath (compared with no rinse), but no significant difference in concentrations between the use of CHG solution without rinse and preimpregnated CHG wipes.In this 2-phase real-world evaluation of chlorhexidine gluconate (CHG) skin concentrations in intensive care unit patients, we found lower skin CHG concentrations when rinsing with water after CHG solution bath (compared with no rinse), but no significant difference in concentrations between the use of CHG solution without rinse and preimpregnated CHG wipes. CHG concentration audits could be useful in assessing the quality of bathing practice, and CHG solution without rinsing may be an alternative to preimpregnated CHG wipes.

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