Glucose therapy of recurrent lactic acidosis

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Abstract

Lactic acidosis not associated with hypoxic states has a high morbidity and mortality. Treatment of this condition has been supportive and the etiology poorly understood. We report a case of recurrent lactic acidosis in a patient with renal and hepatic insufficiency with hypoglycemia which was repeatedly reversed by restoring the glucose concentration to normal. This case and several others in the literature suggest a mechanism for the development of type II B hyper-lactatemia and new approaches for therapy.

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