Orthodontic treatment in patients with congenitally missing teeth can be challenging. In this case report, we describe the treatment of a 15-year-old girl with mild dental crowding and 2 congenitally missing mandibular incisors. The Forsus fatigue-resistant device was used to move the mandible and the mandibular teeth forward. A new balanced and stable occlusion was achieved after treatment. When the treatment plan includes moving the mandibular teeth forward in a patient with mandibular incisor agenesis, the profile and the skeletal and dental features should be carefully scrutinized to ensure that balanced and esthetic results are achieved.