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The objective of this study was to evaluate the effect of a new approach—bimaxillary miniplates-based skeletal anchorage—in the treatment of skeletal Class II malocclusion compared with untreated subjects.The study (miniplates) group comprised 28 patients (14 boys, 14 girls) with skeletal Class II malocclusion due to mandibular retrusion, with a mean age of 11.83 years. After 0.017 × 0.025-in stainless steel archwires were placed in both arches, 4 miniplates were fixed bilaterally, 2 in the maxillary anterior areas and 2 in the mandibular posterior areas, and used for skeletal treatment with elastics. Twenty-four Class II untreated subjects (11 boys, 13 girls), with a mean age of 11.75 years, were included as controls. Skeletal and dental changes were evaluated using pretreatment and posttreatment or observational lateral cephalometric radiographs. The treatment changes were compared with the growth changes observed in the control group using independent t tests.Compared with the minimal changes induced by growth in the control group, the skeletal changes induced by miniplates were more obvious. The mandibular length increased significantly (3 mm), and the mandible moved forward, with a significant restraint in the sagittal position of the maxilla (P <0.001). The overjet correction (−4.26 mm) was found to be a net result of skeletal changes (A-Y-axis = −1.18 mm and B-Y-axis = 3.83 mm). The mandibular plane was significantly decreased by 2.75° (P <0.001).This new technique, bimaxillary miniplates-based skeletal anchorage, is an effective method for treating patients with skeletal Class II malocclusions through obvious skeletal, but minimal dentoalveolar, changes.Bimaxillary miniplate-based skeletal anchorage was used for skeletal Class II malocclusion.Miniplates were fixed in the anterior maxilla and the posterior mandible.Elastics were used to apply bilateral pull force.Compared with controls, the miniplates had a growth-enhancing effect on the mandible.Compared with controls, the miniplates had a restricting effect on the maxilla.This is an effective method for treating skeletal Class II malocclusion.