DIFFERENTIAL CEREBRAL AND NEUROPSYCHOLOGICAL CONSEQUENCES IN DIZYGOTIC TWINS WITH PRENATAL ALCOHOL EXPOSURE

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Abstract

Aim

To relate structural and functional findings in one adolescent dizygotic twin pair with prenatal alcohol exposure.

Method

Neuropsychological and volumetric magnetic resonance studies were carried out on a 13-year-old preterm dizygotic twin pair with prenatal alcohol exposure.

Results

Neuropsychological and brain structural findings differed between the twins. The child with the more affected phenotype had large-scale cognitive deficits and presented significant atrophy in several brain structures. Both subjects had white matter volume reductions relative to the whole cerebral volume.

Conclusion

The neuropsychological and neuroimaging data reflect long-term consequences of prenatal alcohol exposure.

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