To relate structural and functional findings in one adolescent dizygotic twin pair with prenatal alcohol exposure.Method
Neuropsychological and volumetric magnetic resonance studies were carried out on a 13-year-old preterm dizygotic twin pair with prenatal alcohol exposure.Results
Neuropsychological and brain structural findings differed between the twins. The child with the more affected phenotype had large-scale cognitive deficits and presented significant atrophy in several brain structures. Both subjects had white matter volume reductions relative to the whole cerebral volume.Conclusion
The neuropsychological and neuroimaging data reflect long-term consequences of prenatal alcohol exposure.