Final Program
14th Congress of the European Society for Biomedical Research on Alcoholism (ESBRA) September 8-11, 2013 Warsaw, Poland
PL1FOUR DECADES OF RESEARCH ON THE LEVEL OF RESPONSE TO ALCOHOL AS A RISK FACTOR FOR ALCOHOLISM
PL2A NEW GENETIC SUBTYPE OF ALCOHOLISM
PL3ALCOHOL AND CANCER
PL4GLUTAMATE, WHAT ELSE?
S01NURTURING ADDICTION RESEARCH AND HARMONISING ALCOHOLISM TREATMENT IN EUROPE SYMPOSIUM OF THE EUROPEAN FEDERATION OF ADDICTION SOCIETES (EUFAS) I
S01.1A BIBLIOMETRIC ANALYSIS OF EUROPEAN VS. USA RESEARCH IN THE ADDICTION FIELD. RESEARCH ON ALCOHOL, NARCOTICS, PRESCRIPTION DRUG ABUSE, TOBACCO AND STEROIDS 2001–2011
S01.2ALCOHOL INTERVENTION GUIDELINES IN THE UK
S01.3TREATMENT APPROACHES IN EUROPE. A VIEW FROM THE AMPHORA PROJECT
S01.4TREATMENT DECREASES MORTALITY IN ALCOHOL DEPENDENT PATIENTS
S02SEROTONIN SYSTEM IN ALCOHOLISM
S02.1PHARMACOGENETIC APPROACH TO TREATMENT OF ALCOHOL DEPENDENCE WITH ONDANSETRON
S02.2INTERACTIVE EFFECTS OF HTR3A, HTR3B, AND SLC6A4 GENETIC VARIATIONS ON RISK FOR ALCOHOL DEPENDENCE IN INDIVIDUALS OF EUROPEAN DESCENT
S02.3NOVELTY SEEKING AS A PREDICTOR OF DROPOUT FROM THE TREATMENT OF ALCOHOL DEPENDENCE WITH THE 5-HT3 ANTAGONIST ONDANSETRON
S02.4PERSONALIZED TREATMENT MATCHING OF SEROTONERGICS BASED ON 5′-HTTLPR AND DRD4 IN NON-TREATMENT-SEEKING ALCOHOLICS
S03ALCOHOL, CANCER, HEPATITIS AND FATTY LIVER
S03.1ROLE FOR ALTERED CEA PROCESSING BY LIVER CELLS IN ENHANCED COLORECTAL CANCER (CRC) LIVER METASTASIS IN THE ALCOHOLIC
S03.2ALCOHOL INDUCED ALTERATIONS IN HEPATIC HDACS
S03.3EFFECT OF ALCOHOL ON TUMOR PROGRESSION IN DIFFERENT MOUSE MODELS OF HEPATOCELLULAR CARCINOMA
S03.4FAMILIAL NON-ALCOHOLIC STEATOHEPATITIS LEADING TO HEPATOCELLULAR CARCINOMA
S04ALCOHOLIC HEPATITIS ESBRA & NIAAA JOINT SYMPOSIUM
S04.1CLINICAL AND THERAPEUTIC IMPLICATIONS OF INFLAMMATION IN ALCOHOLIC LIVER DISEASE
S04.2INFLAMMATION DRIVEN FIBROGENESIS IN ALD. FIBROGENIC AND INFLAMMATORY SIGNALING MODULATES ALCOHOL EFFECTS IN LIVER
S04.3THE ROLE OF IRON IN ALCOHOL LIVER DISEASE
S04.4EFFECT OF CHRONIC ALCOHOL CONSUMPTION ON NON-ALCOHOLIC STEATOHEPATITIS (NASH)
S04.5Alcoholic hepatitis
S04.6Novel therapeutic targets for alcoholic hepatitis
S05FUNCTIONAL IMPORTANCE OF INHIBITORY AMINO ACIDS IN THE EFFECTS OF ETHANOL
S05.1GLYCINERGIC RESPONSES IN RELATION TO ALCOHOL
S05.2EFFECTS OF LONG-TERM ALCOHOL CONSUMPTION ON GLYCINE RECEPTOR GENE EXPRESSION IN THE RAT CNS
S05.3NEUROPROTECTIVE ROLE FOR TAURINE ANALOGUES IN ALCOHOL ABUSE
S05.4MULTIPLE GABA-A RECEPTOR SUBTYPES IN ALCOHOL-MODULATING EFFECTS OF RO 15-4513
S05.5BRAIN-REGION SPECIFIC MODULATION OF ETHANOL-INDUCED DEPRESSION OF GABAERGIC NEURONS IN THE REWARD SYSTEM BY THE NICOTINE RECEPTOR ANTAGONIST MECAMYLAMINE
S06ARE METABOTROPIC GLUTAMATE RECEPTORS PROMISING TARGETS FOR ALCOHOL ADDICTION?
S06.1MGLU5 RECEPTORS AND EXTINCTION OF DRUG-SEEKING
S06.2MODULATION OF SENSITIVITY TO ALCOHOL INTEROCEPTIVE CUES BY MGLURS
S06.3INFRALIMBIC MGLUR2 DEFICIT AS A KEY MECHANISM FOR ALCOHOL ADDICTION
S06.4THE ROLE OF MGLUR5 IN NOVELTY- SEEKING BEHAVIORS AND THE ESCALATION OF ALCOHOL DRINKING AFTER ABSTINENCE IN MICE
S07NONINVASIVE SCREENING TOOLS FOR LIVER CIRRHOSIS IN ADDICTED PATIENTS
S07.1INDIVIDUAL CIRRHOSIS SCREENING VIA LIVER STIFFNESS
S07.2LIVER STIFFNESS AND CONTROLLED ATTENUATION PARAMETER MEASUREMENTS USING SHEAR WAVE BASED QUANTITATIVE ELASTOGRAPHY
S07.3IS THERE A ROLE FOR HISTOLOGY IN THE PREDICTION OF LONG-TERM MORTALITY IN ALD?
S07.4WHAT SHOULD BE USED TO MEASURE LIVER STIFFNESS
S07.5LIVER STIFFNESS AND SERUM MARKER
S08SUBGROUPS OF ADDICTION AND THEIR SPECIAL TREATMENT
S08.1MECHANISMS OF CRAVING
S08.2LAT TYPOLOGY STRUCTURE IN SERBIAN ALCOHOL ADDICTS - AN ANALYSIS OF THERAPEUTICALLY RELEVANT ITEMS
S08.3LESCH TYPOLOGY AND TEMPERAMENT IN OPIOID DEPENDENCE
S08.4CUT DOWN DRINKING - A SPECIAL TREATMENT?
S09GENDER DIFFERENCES IN ALCOHOLISM I
S09.1FEMALE ALCOHOLISM, CLINICAL DIFFERENCES AND DIFFERENCES IN THERAPY
S09.2GENDER DIFFERENCES IN ALCOHOL-ASSOCIATED BRAIN ATROPHY
S09.3GENDER RISK IN ALCOHOL DEPENDENCE
S09.4DIFFERENCES IN SUICIDAL BEHAVIOR AMONG MALE AND FEMALE ALCOHOLICS
S10EMERGING DRUGS FOR TREATING ALCOHOL USE DISORDERS
S10.1THE ROLE OF GUT-BRAIN HORMONES IN REWARD FROM ADDICTIVE DRUGS
S10.2THE MONOAMINE STABILIZER (-)-OSU6162 - A POTENTIAL NOVEL TREATMENT FOR ALCOHOL USE DISORDER
S10.3PRECLINICAL EVIDENCE ON THE “ANTI-ALCOHOL” PROPERTIES OF THE POSITIVE ALLOSTERIC MODULATORS OF THE GABAB RECEPTOR
S10.4PRECLINICAL STUDIES ON ALCOHOL ADDICTION
S11ALCOHOL AS A MODULATOR OF LIVER DISEASE PROGRESSION ESBRA & EASL JOINT SYMPOSIUM
S11.1IMPACT OF ALCOHOL DRINKING ON THE PROGRESSION AND TREATMENT OF CHRONIC HEPATITIS C AND B
S11.2DRUGS IN ALCOHOL ABUSERS
S11.3THE OBESE ALCOHOLIC
S11.4HEPATOCELLULAR CARCINOMA IN ALCOHOLIC CIRRHOSIS
S12THE ROLE OF PSYCHOSOCIAL FACTORS IN THE DEVELOPMENT OF ALCOHOL USE AND RELATED PROBLEMS IN YOUNG ADULTHOOD
S12.1SOCIAL ROLE TRANSITIONS AND YOUNG ADULT ALCOHOL AND MARIJUANA USE
S12.2ALCOHOL USE OVER TIME IN AMERICAN AND SWEDISH YOUNG ADULTS
S12.3TWO PATHWAYS TO ALCOHOL
S13MULTIPLE HITS IN THE PATHOGENESIS OF ALCOHOLIC LIVER DISEASE
S13.1DIFFERENT ALD SPECTRA PRODUCED BY INTERACTIONS OF ALCOHOL, WESTERN DIET, BINGE, AND HEPATITIS VIRUS
S13.2FUNCTIONAL ROLE OF THE ENDOCANNABINOID SYSTEM IN ALCOHOLIC LIVER FIBROSIS
S13.3CYTOCHROME P450 2E1 AND OXIDATIVE STRESS IN THE PROGRESSION OF ALCOHOLIC LIVER DISEASE
S13.4CHRONIC STRESS EXACERBATES ETHANOL-INDUCED TISSUE INJURY IN GUT AND LIVER
S13.5ALCOHOL AND HYPOXIA
S14THE HEALTH AND BEHAVIOURAL CONSEQUENCES OF ALCOHOL HANGOVER
S14.1BEHAVIOURAL CONSEQUENCES OF THE ALCOHOL HANGOVER - PRELIMINARY FINDINGS
S14.2PROSPECTIVE MEMORY DEFICITS ASSOCIATED WITH A STATE OF ALCOHOL HANGOVER
S14.3LAPSES OF ATTENTION DURING DRIVING IN THE ALCOHOL HANGOVER STATE
S14.4BIOLOGICAL, PSYCHOLOGICAL, AND BEHAVIORAL CORRELATES OF THE ALCOHOL HANGOVER
S15ALCOHOL DEPENDENCE AND NEUROENDOCRINOLOGY – NEW FINDINGS AND PERSPECTIVES
S15.1DYREGULATED LEPTIN LEVELS IN HEAVY DRINKING ALCOHOL-DEPENDENT SUBJECTS AND THE LOSS OF METABOLIC CONTROL
S15.2THE ASSOCIATION OF THE APPETITIVE PEPTIDE ACETYLATED GHRELIN WITH ALCOHOL CRAVING IN EARLY ABSTINENT ALCOHOL DEPENDENT INDIVIDUALS
S15.3LONG-TERM ETHANOL EFFECTS ON ACUTE STRESS RESPONSES
S15.4ACUTE ETHANOL EFFECTS ON THE HYPOTHALAMIC-PITUITARY-ADRENAL SYSTEM IN HEALTHY SUBJECTS
S16GUT MICROBIOTA, INTESTINAL BARRIER FUNCTION, ENDOTOXEMIA AND ALCOHOLIC LIVER INJURY
S16.1CHRONIC ALCOHOL INDUCED PATHOGENIC ALTERATIONS IN THE INTESTINAL MICROBIOME AND LIVER DISEASE AND THE EFFECT OF LACTOBACILLUS RHAMNOSUS GG TREATMENT
S16.2ALDH2 DEFICIENCY AGGRAVATES ETHANOL-INDUCED GUT BARRIER DYSFUNCTION AND LIVER INJURY
S16.3ETHANOL AND DIETARY UNSATURATED FAT-INDUCED INTESTINAL AND LIVER INJURY IN AN ANIMAL MODEL OF ALD
S16.4CHRONIC ALCOHOL EXPOSURE ALTERS GASTROINTESTINAL METABOLITES IN ASSOCIATION WITH GUT LEAKINESS AND LIVER INJURY IN RATS CHRONICALLY EXPOSED TO ALCOHOL
S17ALCOHOL DEPENDENCE AND SUICIDAL BEHAVIOR - AN INTERNATIONAL PERSPECTIVE
S17.1CO-MORBID ALCOHOL DEPENDENCE AND ANXIETY DISORDER INCREASE THE RISK OF SUICIDAL BEHAVIOR
S17.2HISTORY OF SUICIDE ATTEMPT AS A PROGNOSIC FACTOR FOR TREATMENT OUTCOME IN ALCOHOL-DEPENDENT INDIVIDUALS
S17.3HISTORY OF CHILD ABUSE AND SUICIDE ATTEMPTS IN ALCOHOL DEPENDENT PATIENTS
S17.4SUICIDAL IDEATION AND BEHAVIOR IN JAPANESE PATIENTS WITH ALCOHOL DEPENDENCE
S18FETAL ALCOHOL SPECTRUM DISORDERS
S18.1HISTORICAL UNDERSTANDING OF ALCOHOL IN PREGNANCY AND ITS IMPACT
S18.2THE COLLABORATIVE INITIATIVE ON FETAL ALCOHOL SPECTRUM DISORDERS - AN OVERVIEW AND UPDATE
S18.3ETHANOL ALTERS HUMAN EMBRYONIC STEM CELLS DIFFERENTIATION TOWARD NEURAL PROGENITORS (NPS), ALTERS CELL FATE AND IMPAIRS NPS TRANSFORMATION INTO MATURE NEURAL CELLS
S18.4UNDERSTANDING OF MECHANISMS UNDERLYING BRAIN ABNORMALITY IN FASD AND ITS TRANSLATIONAL APPROACH
S18.5CHOLINE AS A TREATMENT FOR FETAL ALCOHOL SPECTRUM DISORDERS
S19LIVER TRANSPLANTATION IN PATIENTS WITH ALCOHOLIC LIVER DISEASE
S19.1LIVER TRANSPLANTATION FOR PATIENTS WITH ALCOHOL-INDUCED CIRRHOSIS
S19.2PUBLIC ATTITUDES TOWARDS LIVER DONATION IN ALCOHOLICS
S19.3SPECIFIC PRE- AND POST-TRANSPLANT PROBLEMS IN ALCOHOLIC LIVER GRAFT RECIPIENTS
S19.4EXTENDING LIVER TRANSPLANTATION TO PATIENTS WITH SEVERE ALCOHOLIC HEPATITIS - CHANGE OF PARADIGM
S20MODULATING EFFECTS OF ALCOHOL AND CANNABIS USE ON OTHER DRUG USE
S20.1ASSOCIATIONS BETWEEN ALCOHOL AND CANNABIS USE AND QUALITY OF LIFE
S20.2DRUG AND ALCOHOL USE IN FREQUENT AND INFREQUENT CANNABIS USERS
S20.3AMOUNT AND CONSEQUENCES OF ALCOHOL DRINKING ARE MODULATED BY EVER USING CIGARETTES AND CANNABIS. A COMPARISON BETWEEN SWEDEN AND US
S20.4THE ROLE OF CANNABIS, BENZODIAZEPINES AND ALCOHOL IN THE TREATMENT OF OPIATE DEPENDENCE
S21TOWARD A BETTER UNDERSTANDING OF THE SPECTRUM OF FETAL ALCOHOL SPECTRUM DISORDERS AND THE ROLE OF MATERNAL NUTRITION IN MODIFYING FETAL RISK
S21.1EXTENDING THE SPECTRUM OF STRUCTURAL DEFECTS ASSOCIATED WITH PRENATAL ALCOHOL EXPOSURE
S21.2MATERNAL ALCOHOL CONSUMPTION DURING PREGNANCY, NUTRITIONAL STATUS AND IMPACT ON INFANT OUTCOMES
S21.3MICRONUTRIENT SUPPLEMENTS CAN MITIGATE THE TERATOGENIC EFFECTS OF PRENATAL ALCOHOL EXPOSURE ON UKRAINIAN INFANTS AT 6 MONTHS
S21.4THE IMPACT OF MICRONUTRIENT SUPPLEMENTATION IN ALCOHOL-EXPOSED PREGNANCIES ON INFORMATION PROCESSING SKILLS IN UKRAINIAN INFANTS
S22LIVER TRANSPLANTATION
S22.1ASSESSING DRINKING STATUS IN LIVER TRANSPLANT PATIENTS WITH ALCOHOLIC LIVER DISEASE
S22.2RISK FOR RELAPSE OF ALCOHOL USE AFTER LIVER TRANSPLANTATION FOR ALCOHOLIC LIVER DISEASE
S22.3LIVER TRANSPLANTATION FOR ALCOHOLIC LIVER DISEASE
S22.4LIVER TRANSPLANTS IN SPAIN
S22.5LIVER TRANSPLANTATION OF ALCOHOL-DEPENDENT SUBJECTS IN GERMANY
S23BINGE DRINKING IN YOUTHS
S23.1A PROSPECTIVE HIGH-RISK STUDY ON NEUROCOGNITIVE PREDICTORS OF AND NEUROCOGNITIVE EFFECTS OF BINGE-DRINKING IN EARLY ADOLESCENCE
S23.2BINGE DRINKING INFLUENCES THE CEREBRAL PROCESSING OF AFFECTIVE VOCALIZATIONS
S23.3EFFECTS OF BINGE DRINKING ON PREFRONTAL EXECUTIVE FUNCTION
S23.4BINGE DRINKERS INCREASE CORTICAL ACTIVITY TO COPE WITH WORKING MEMORY TASK
S24NEW DEVELOPMENTS IN THE TREATMENT OF ALCOHOL USE DISORDERS
S24.1ACCEPTANCE AND COMMITMENT THERAPY (ACT)
S24.2SUPPORTIVE TEXT MESSAGING FOR DEPRESSION AND COMORBID ALCOHOL USE DISORDER
S24.3COMPUTERISED COGNITIVE BEHAVIOURAL THERAPY FOR ALCOHOL USE DISORDER
S24.4ABSTINENCE OR REDUCTION – THE DEBATE
S25UNITY IN DIVERSITY APSAAR, LASBRA & ESBRA JOINT SYMPOSIUM
S25.1GENETIC ASSOCIATIONS AND CRAVING IN ALCOHOLIC IN-PATIENTS
S25.2ENVIRONMENTAL ENRICHMENT BLOCKS ETHANOL-INDUCED BEHAVIORAL SENSITIZATION AND DECREASES ETHANOL INTAKE
S25.3GABA-A RECEPTORS, ALCOHOL AND RO 15-4513
S25.4PROFILES OF GABA-A RECEPTOR SUBTYPES IN HUMAN ALCOHOLIC BRAIN
S26PERSISTENT EFFECTS OF BINGE DRINKING ON ADOLESCENT BRAIN
S26.1EFFECTS OF ADOLESCENT ETHANOL EXPOSURE ON BRAIN SYNCHRONY, BEHAVIOR, DTI VOLUMES, NEUROGENESIS AND CHOLINE ACETYL TRANSFERASE
S26.2ADOLESCENT BINGE DRINKING INDUCES PERSISTENT HMGB1-TLR-RAGE SIGNALING
S26.3PERSISTENT EFFECTS OF BINGE DRINKING ON ADOLESCENT BRAIN
S26.4LONG-TERM COGNITIVE DYSFUNCTIONS IN ADOLESCENT RATS WITH BINGE DRINKING ARE ASSOCIATED WITH NEUROIMMUNE ACTIVATION AND MYELIN DYSFUNCTION
S27INNOVATIVE TECHNIQUES IN HUMAN LABORATORY ALCOHOL RESEARCH
S27.1THE COMPUTER-ASSISTED INFUSION SYSTEM (CAIS) FOR EXPERIMENTAL ETHANOL ADMINISTRATION IN HUMANS
S27.2CHARACTERIZATION OF OPERANT INTRAVENOUS ALCOHOL SELF-ADMINISTRATION IN HUMANS
S27.3STUDYING THE ROLE OF FEEDING-RELATED PATHWAYS IN ALCOHOLISM VIA HUMAN LABORATORY STUDIES
S27.4SUBJECTIVE RESPONSES TO ALCOHOL IN THE LAB PREDICT NEURAL RESPONSES TO ALCOHOL CUES
S27.5COGNITIVE BIAS MODIFICATION (CBM)
S28ALCOHOL ABUSE COMORBIDITY ESBRA, APSAAR & JMSAS JOINT SYMPOSIUM
S28.1CLINICAL FEATURES OF CO-MORBID ALCOHOL DEPENDENCE, ANXIETY AND DEPRESSION
S28.2BASIC ASPECTS OF ALCOHOL USE DISORDER COMORBID WITH DEPRESSIVE DISORDER
S28.3ALCOHOL COMORBIDITY IN HEPATIC AND GASTROENTEROLOGICAL DISORDERS
S28.4EFFECT OF ALCOHOL COMORBIDITIES IN METABOLISM IN THE CARDIOVASCULAR SYSTEM INCLUDING BLOOD PRESSURE
S29YOUNG INVESTIGATORS SYMPOSIUM
S29.1CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC ETHANOL ADMINISTRATION
S29.2ROLE OF ALCOHOL IN THE METABOLIC DISORDERS CAUSED BY HEPATITIS C VIRUS INFECTION
S29.3DECISION-MAKING, AFFECTIVE TEMPERAMENT AND COGNITIVE FUNCTIONS IN PATIENTS DETOXIFIED FROM ALCOHOL
S29.4EFFECTS OF DRUGS USED IN PHARMACOTHERAPY OF ALCOHOL ADDICTION ON OPERANT SENSATION SEEKING IN MICE
S29.5HAPLOTYPE ANALYSIS OF TWO POLYMORPHISMS IN ANKK1 GENE IN HOMOGENOUS SUBGROUPS OF ALCOHOL DEPENDENT SUBJECTS
S29.6GENETIC VARIANTS IN THE ALCOHOL DEHYDROGENASE GENES ADH1B AND ADH1C INDEPENDENTLY AFFECT SUSCEPTIBILITY TO ALCOHOL DEPENDENCE SYNDROME IN A BRITISH AND IRISH POPULATION
S30GENDER DIFFERENCES IN ALCOHOL DEPENDENCE II
S30.1GENDER COMPARISON OF TYPOLOGICAL CLASSIFICATIONS OF ALCOHOL DEPENDENT PERSONS
S30.2DIFFERENCES INDUCED BY ALCOHOL METABOLISM IN MALE AND FEMALES ALCOHOL ABUSERS BY COMPARISON TO CONTROLS
S30.3GENDER ASPECTS IN ADDICTION TREATMENT
S30.4GENDER COMPARISON OF RISKS AND SYMPTOM SEVERITY ASSOCIATED WITH ALDH2 POLYMORPHISMS IN ALCOHOL DEPENDENT MEN, WOMEN AND CONTROLS
S31EPIGENETIC MECHANISMS OF ALCOHOLISM
S31.1ADOLESCENT INTERMITTENT ETHANOL-INDUCED HISTONE MODIFICATIONS AND DNA DEMETHYLATION
S31.2IS THERE A FUTURE FOR USING HDAC INHIBITORS IN ALCOHOL DEPENDENCE?
S31.3GENETIC AND ENVIRONMENTAL RISKS FOR PATTERNS OF ALCOHOL USE FROM ADOLESCENCE THROUGH EARLY ADULTHOOD
S31.4PRENATAL ETHANOL-INDUCED HYPERMETHYLATION OF PROOPIOMELANOCORTIN GENE TRANSMITS THROUGH GERMLINE
S32RECENT ADVANCES IN LABORATORY DIAGNOSTICS OF ALCOHOL AND DRUG USE AND DEPENDENCE. APPLICATION OF NEW BIOMARKERS INTO CLINICAL PRACTICE
S32.1ROLE OF SOME GENETIC FACTORS IN THE ONSET AND COURSE OF ALCOHOL DEPENDENCE
S32.2SIGNIFICANCE OF ACE, 5HTTLPR AND BDNF GENES INTERACTIONS AS PREDICTORS OF THE RISK OF THE ONSET OF ALCOHOL PROBLEMS. DATA FROM POLISH SAMPLE OF ALCOHOL-DEPENDENT PATIENTS
S32.3DEVELOPMENTS IN LABORATORY TECHNIQUES FOR DETECTION AND DETERMINATION OF OLD AND NEW SYNTHETIC DRUGS OF ABUSE
S32.4SALIVARY BIOMARKERS OF ALCOHOL ABUSE
SAT1ALCOHOL DEPENDENCE - FROM RISK TO REALITY (LUNDBECK)
SAT1.1RISK FACTORS FOR ALCOHOL DEPENDENCE
SAT1.2AN EXTENSION OF THE CURRENT TREATMENT PARADIGM FOR ALCOHOL DEPENDENCE
SAT1.3CLINICAL DATA SUPPORTING THE BENEFIT OF A PATIENT-CENTRED APPROACH IN THE TREATMENT OF ALCOHOL DEPENDENCE
SAT2SODIUM OXYBATE, A BREAKTHROUGH TREATMENT OF ALCOHOL WITHDRAWAL SYNDROME AND MAINTENANCE OF ALCOHOL ABSTINENCE (D&A)
SAT2.1Sodium Oxybate in Alcohol Withdrawal – Results from the GATE 1 Study
SAT2.2SODIUM OXYBATE IN THE PREVENTION OF ALCOHOL RELAPSES IN ALCOHOL DEPENDENT PATIENTS (GATE 2 STUDY)
SAT2.3PHARMACODYNAMIC INTERACTIONS OF A SOLID FORMULATION OF SODIUM OXYBATE AND ALCOHOL IN HEALTHY VOLUNTEERS
SAT2.4A RETROSPECTIVE STUDY ON THE USE OF SODIUM OXYBATE IN NORTHERN ITALY
O1FREE ORAL COMMUNICATIONS 1
O1.1DYNAMIC REGULATION OF MIR-9 PATHWAYS BY ALCOHOL
O1.2NEUROINFLAMMATORY PARP PATHWAYS IN ETHANOL-DEPENDENT NEURODEGENERATION
O1.3BINGE-LIKE DRINKING IN SARDINIAN ALCOHOL-PREFERRING RATS EXPOSED TO AN UNPREDICTABLE SCHEDULE OF LIMITED ACCESS TO MULTIPLE ALCOHOL CONCENTRATIONS
O1.4REHABILITATION AND NEUROPROTECTION
O2FREE ORAL COMMUNICATIONS 2
O2.1CONTINUING TREATMENT IN SPITE OF RELAPSES
O2.2THE IMPACT OF TREATMENT DURATION IN ALCOHOLISM
O2.3EFFICACY OF ACAMPROSATE FOR THE TREATMENT OF ALCOHOL DEPENDENCE LONG AFTER RECOVERY FROM WITHDRAWAL SYNDROME
O2.4GOAL
O2.5EFFECTS OF BACLOFEN ON NEUROBIOLOGICAL CORRELATES OF ALCOHOL DEPENDENCE
O3FREE ORAL COMMUNICATIONS 3
O3.1ROLE OF GUT MICROBIOTA IN THE BIOLOGICAL AND BEHAVIORAL CONTROL OF ALCOHOL-DEPENDENCE
O3.2RAPID IMPACT OF ALCOHOL WITHDRAWAL ON BIOMARKERS OF LIVER LESIONS (FIBROTEST®)
O3.3ELEVATION OF SERUM ENDOCANNBINOID LEVELS IN ALCOHOLIC AND HEPATITIS C VIRUS-RELATED LIVER DISEASE DUE TO DECREASED EXPRESSION OF ENDOCANNABINOID DEGRADING ENZYMES
O3.4THE PNPLA3 I148M MUTATION SIGNIFICANTLY INCREASES THE RISK OF DEVELOPING ALCOHOL-RELATED CIRRHOSIS IN ALCOHOL DEPENDENT INDIVIDUALS
O4FREE ORAL COMMUNICATIONS 4
O4.1BRIEF MOTIVATIONAL INTERVENTION TO REDUCE ALCOHOL CONSUMPTION IN YOUNG PATIENTS IN A FRENCH EMERGENCY DEPARTMENT
O4.2HARMFUL ALCOHOL CONSUMPTION IN HEALTH-WORKERS
O4.3BRIEF INTERVENTION IN PRIMARY HEALTH CARE FOR ALCOHOL USERS
O4.4UNIVERSAL SCHOOL-BASED PREVENTION INTERVENTION AND ALCOHOL USE
O5FREE ORAL COMMUNICATIONS 5
O5.1THE PROHIBITION OF DISTILLATES IN THE CZECH REPUBLIC IN REACTION ON METHYL-ALCOHOL ON LEGAL AND ILLEGAL MARKETS IN 2012
O5.2MORTALITY AMONG ALCOHOL TREATMENT PATIENTS IN LATVIA
O5.3ALCOHOL AFFORDABILITY AND ALCOHOL RELATED MORTALITY IN BELARUS
O5.4ALCOHOL POLICY CHANGE IN BULGARIA
O5.5ALCOHOL ATTRIBUTABLE FRACTION OF CARDIOVASCULAR MORTALITY IN RUSSIA
O6FREE ORAL COMMUNICATIONS 6
O6.1SEXUAL ORIENTATION AND DRUG OF CHOICE
O6.2SUSCEPTIBILITY OF AGE AND GENDER TO INTERMITTENT ALCOHOL ABUSE
O6.3HIGH EDUCATIONAL LEVELS AS PROTECTIVE FACTOR AGAINST DRUG AND ALCOHOL CONSUMPTION
O6.4AGE OF ONSET, PHYSICAL AND MENTAL HEALTH AND SOCIAL FUNCTIONING IN OLDER ALCOHOL-DEPENDENT INPATIENTS
O7FREE ORAL COMMUNICATIONS 7
O7.1ALCOHOL USE DISORDERS IN PATIENTS SEEKING TREATMENT FOR CANNABIS DEPENDENCE
O7.2MODELING EFFECTIVENESS OF INPATIENT ALCOHOL DETOXIFICATION
O7.3HOW TO PREVENT RELAPSES FURTHER TO AN INPATIENT ALCOHOL DETOXIFICATION
O7.4MODELING OF COMORBID MENTAL DISORDERS
BASIC RESEARCH
P01PROTECTIVE EFFECTS OF AMINO ACIDS ON THE HEART IN CHRONICALLY ALCOHOL TREATED RATS
P02DYSFUNCTIONS IN PROTEIN DEGRADATION IN ALCOHOL-INDUCED NEUROINFLAMMATION AND BRAIN DAMAGE
P03ALTERED BINGE-LIKE ETHANOL CONSUMPTION IN CORTICOTROPIN RELEASING FACTOR BINDING PROTEIN-DEFICIENT MICE
P04VOLUNTARY ALCOHOL DRINKING BY ALCOHOL-PREFERRING RATS INCREASES BRAIN FUNCTIONAL ACTIVITY ASSESSED BY MANGANESE-ENHANCED MRI
P05FURTHER CHARACTERIZATION OF THE “ANTI-ALCOHOL” EFFECTS OF THE POSITIVE ALLOSTERIC MODULATORS OF THE GABAB RECEPTOR, GS39783 AND RAC-BHFF
P06REDUCING EFFECT OF DIFFERENT ALCOHOL-RELATED BEHAVIORS BY THE DOPAMINE β-HYDROXYLASE INHIBITOR, NEPICASTAT, IN RATS
P07REDUCING EFFECT OF THE CHINESE MEDICINAL HERB, SALVIA MILTIORRHIZA, ON ALCOHOL REINFORCING AND MOTIVATIONAL PROPERTIES IN SARDINIAN ALCOHOL-PREFERRING RATS
P08ETHANOL AFFECTS HEPATITIS C PATHOGENESIS
P09ANXIETY-LIKE BEHAVIOR AND BDNF LEVELS AS MARKERS OF VULNERABILITY TO ETHANOL-INDUCED BEHAVIORAL SENSITIZATION
P10EFFECTS OF PANTHENOL AND CARNITINE ADMINISTRATION ON THE LIVER DAMAGE PRODUCED BY ALCOHOL
P11THE MONOAMINE STABILIZER (-)-OSU6162 RESTORES DOWN-REGULATED DOPAMINE OUTPUT IN NACC INDUCED BY LONG-TERM VOLUNTARY ETHANOL CONSUMPTION
P12REDUCTION IN CENTRAL H2O2 LEVELS PREVENTS VOLUNTARY ETHANOL INTAKE IN MICE
P13ROLE OF CA2 + /CALMODULIN ON ETHANOL INTAKE
P14REDUCTION OF BRAIN H2O2 LEVELS BLOCKS ETHANOL-RELATED DECREASE OF BLOOD LUTEINIZING HORMONE LEVELS IN MICE
P15ASSOCIATIONS BETWEEN CORTICOSTEROIDS, ALCOHOL-MEDIATED TESTOSTERONE ELEVATION AND ALCOHOL DRINKING
P16EFFECT OF EARLY LIFE STRESS AND ETHANOL CONSUMPTION ON POMC IN RAT HYPOTHALAMUS
P17MORPHO-FUNCTIONAL STATE OF BRAIN HISTAMINERGIC NEURONS FOLLOWING 6-MONTH'S ALCOHOL CONSUMPTION IN RATS
P18A MODEL OF INTERMITTENT ACCESS TO ALCOHOL IN GROUP-HOUSED C57BL/6J MICE
P19EXPRESSION OF α-SYNUCLEIN SPLICE VARIANTS AND MIRNA FOLLOWING CHRONIC AND CHRONIC-INTERMITTENT ETHANOL TREATMENT
P20WORKING MEMORY DEFICITS IN THE MATURE RAT FOLLOWING BINGE ETHANOL EXPOSURE IN THE NEONATE
P21CHRONIC ETHANOL INTAKE-INDUCED EPIGENETIC MODIFICATIONS AT BDNF GENE LEVEL IN THE MOUSE HIPPOCAMPUS
TREATMENT
P22NALTREXONE SIGNIFICANTLY REDUCES PERCENTAGE OF DRINKING DAYS, NUMBER OF DRINKS PER DRINKING DAYS AND ALCOHOL CRAVING - RESULTS OF THE META-ANALYSIS
P23DEMOGRAPHICS AND BASELINE CHARACTERISTICS OF THE NALMEFENE PHASE 3 PROGRAMME STUDY POPULATION
P24LONG-TERM EFFICACY OF NALMEFENE AS-NEEDED IN ALCOHOL DEPENDENT PATIENTS WITH HIGH DRINKING RISK LEVELS
P25ESENSE1 - EFFICACY OF NALMEFENE AS-NEEDED IN ALCOHOL DEPENDENT PATIENTS WITH HIGH DRINKING RISK LEVELS
P26ESENSE2 - EFFICACY OF NALMEFENE AS-NEEDED IN ALCOHOL DEPENDENT PATIENTS WITH HIGH DRINKING RISK LEVELS
P27SATISFACTION OF PATIENTS WITH ALCOHOL DEPENDENCE TREATED IN A PSYCHIATRIC OUTPATIENT SERVICE
P28EFFECT OF ACAMPROSATE ON SLEEP DISTURBANCES IN ALCOHOLISM
P29MIFEPRISTONE REDUCES STRESS-INDUCED REINSTATEMENT OF ETHANOL-SEEKING
P30GATE 2 STUDY
P31EFFECTS OF D-PENICILLAMINE IN COMBINATION WITH NALTREXONE IN RELAPSE-LIKE DRINKING IN RATS
P32FEASIBILITY OF AS-NEEDED USE OF NALMEFENE IN THE TREATMENT OF ALCOHOL DEPENDENCE
P33LONG-TERM ALCOHOL CONSUMPTION AND CLINICAL EVOLUTION OF ALCOHOL-DEPENDENT PATIENTS INITIATING TREATMENT
P34PATTERNS OF TREATMENT AND MAINTENANCE OF EFFECT IN ALCOHOL-DEPENDENT PATIENTS
P35INFLUENCE OF THERAPEUTIC WORKING ALLIANCE ON TREATMENT OUTCOME IN ALCOHOL USE DISORDERED PATIENTS
P36HIGH LEVEL OF BZDS IN PATIENTS AFTER ALCOHOL WITHDRAWAL TREATMENT - AN INCOMPLETE DETOXIFICATION?
P37POSSIBLE HAZARD OR A BENEFIT? BZD AND SIMILAR SUBSTANCES DETOX IN PATIENTS OVER 65 YEARS OLD AGE
COMORBIDITY
P38MEDIATING ROLE OF ALCOHOL IN THE RELATION BETWEEN SOCIAL ANXIETY, DEPRESSION AND CANNABIS AMONG ADOLESCENTS
P39FUNCTIONAL AND DYSFUNCTIONAL RUMINATION IN ALCOHOL DEPENDENCE
ALCOHOL LIVER DISEASE
P40FIBROSIS ASSESSMENT IN ALCOHOLIC LIVER DISEASE USING THE SIEMENS ENHANCED LIVER FIBROSIS (ELF) TEST
P41MECHANISM OF HEPATOCYTE APOPTOSIS SUPERINDUCTION TRIGGERED BY TGF-β AND ETHANOL
P42REGULATION OF PATATINE-LIKE PHOSPOLIPASE DOMAIN-CONTAINING PROTEIN-3 (PNPLA3) EXPRESSION BY FATTY ACIDS AND ALCOHOL IN VITRO AND IN VIVO
P43ABSTINENCE CAN LEAD TO UNDERESTIMATION OF LIVER FIBROSIS BY FIBROSCAN® IN FORMER HEAVY DRINKERS
P44DAMAGING EFFECT OF FREE FATTY ACIDS AND ALCOHOL ON HEPATIC MITOCHONDRIAL FUNCTION
P45HISTOLOGICAL HEPATOCYTE DAMAGE PRECEDES STEATOSIS IN ALD PATIENTS WITH GENETIC VARIANT L148M IN PNPLA3
P46M65 IS A HIGHLY SENSITIVE MARKER OF ALCOHOLIC STEATOHEPATITIS
P47PNPLA3 GENE POLYMORPHISM IN SEVERE ACUTE ALCOHOLIC HEPATITIS
P48AMINO ACIDS CAN PREVENT ETHANOL-INDUCED OXIDATIVE STRESS IN THE LIVER
PSYCHOLOGY AND MARKERS
P49HIGHER CUE REACTIVITY IN BOYS BINGE DRINKERS AS REVEALED BY EVENT RELATED POTENTIALS
P50SIMILARITY AND DISPARITY BETWEEN INTERNET ADDICTION AND ALCOHOL DEPENDENCE
P51DISSOCIATION BETWEEN AFFECTIVE AND COGNITIVE EMPATHY IN ALCOHOLISM
P52THE “READING THE MIND IN THE EYES” TEST AS A NEW WAY TO EXPLORE COMPLEX EMOTIONS DECODING IN ALCOHOL DEPENDENCE
P53RELATIONSHIP BETWEEN NOVELTY SEEKING AND STIMULANT EFFECTS OF ETHANOL
P54SEPARATING AUTOMATIC AND INTENTIONAL PREPOTENT RESPONSE INHIBITIONS IN ALCOHOL-DEPENDENT INDIVIDUALS
P55PREFRONTAL EEG THETA ACTIVITY RELATED TO COGNITIVE CONTROL AND RESPONSE INHIBITION IN YOUNG BINGE DRINKERS
P56ANALYSIS OF FATTY ACID ETHYL ESTERS IN MECONIUM AS POSSIBILE MARKERS OF PRENATAL ALCOHOL EXPOSURE
P57PERFORMANCE OF BINGE-DRINKERS ON A VERBAL LEARNING TASK
P58PSYCHOPHYSIOLOGICAL PROCESSES INVOLVED IN ALCOHOL DEPENDENCE
P59COMPARISON OF BLOOD BDNF LEVEL IN PATIENTS WITH ALCOHOL-DEPENDENCE, DEPRESSION AND HEALTHY CONTROLS
P60THE PERIPHERAL CYTOKINE PROFILE IN ALCOHOL DETOXIFICATION
P61DEFICITS IN AUTOBIOGRAPHICAL MEMORY AND AUTONOETIC AWARENESS IN ALCOHOL-DEPENDENT SUBJECTS
P62ASSESSING THE SEDATIVE AND STIMULANT EFFECTS OF ALCOHOL IN A BALANCED PLACEBO DESIGN
P63HIGH AND LOW CORTISOL RESPONDERS TO STRESS SHOW DIFFERENT SUBJECTIVE RESPONSES TO ALCOHOL
P64RISK-TAKING AND STRESS ARE POSITIVELY ASSOCIATED WITH AMPHETAMINE-INDUCED DOPAMINE RELEASE IN HUMANS
P65DRD2 METHYLATION IS ASSOCIATED WITH ALCOHOL DEPENDENCE PHENOTYPES AND DRD2 MRNA IN THE BRAIN
P66NETWORK CONNECTIVITY IN ADOLESCENTS
P67QUANTITATIVE MEASUREMENT OF UPPER LIMB TREMOR IN ALCOHOL-DEPENDENT PATIENTS
P68SACCADIC LATENCY INCREASE IN ALCOHOL-DEPENDENT PATIENTS
EPIDEMIOLOGY
P69ALCOHOL AND MEDICINES CONSUMPTION IN FIRST-YEAR COLLEGE STUDENTS
P70“BEER” ALCOHOLISM IN RUSSIA
P71TRAUMA AND PTSD IN AN AMERICAN INDIAN COMMUNITY
P72USE OF ALCOHOL AND SURROGATES BY RESIDENTS OF A TYPICAL BELARUS CITY
P73VIRTUAL ALCOHOL EXPOSURE
P74BINGE DRINKING, ALCOHOL ABUSE AND DEPENDENCE
P75MODE OF ALCOHOL USE AND AWARENESS AMONG ADOLESCENTS IN CRETE THAT PARTICIPATED IN PRIMARY PREVENTION INCENTIVE
P76TEMPERAMENT AND LESCH TYPOLOGY IN THE CONTEXT OF ALCOHOL AND HEROIN DEPENDENCE
P77LIFETIME SMOKING RATES AMONG ALCOHOL DEPENDENT PATIENTS IN CRETE, GREECE
P78VIP (VERY IMPORTANT PATIENT) PROJECT
P79DESIGN OF THE ODHIN FIVE COUNTRY STUDY - IMPLEMENTING BRIEF INTERVENTIONS FOR HEAVY DRINKING IN PRIMARY HEALTH CARE
P80IMPLEMENTING BRIEF INTERVENTIONS FOR HEAVY DRINKING IN PRIMARY HEALTH CARE - ODHIN BASELINE AND PRELIMINARY OUTCOME RESULTS
P81SCIENTIFIC CHALLENGES OF EUROPEAN IMPLEMENTATION RESEARCH – EXPERIENCES FROM THE ODHIN FIVE COUNTRY STUDY ON IMPLEMENTING BRIEF INTERVENTIONS FOR HEAVY DRINKING IN PRIMARY HEALTH CARE
Author Index