Preferences and Utilities of Health Outcomes and Treatments Associated with Head and Neck Cancer: A Systematic Review


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Abstract

As a result of increased patient knowledge and autonomy, patient input into treatment decisions is becoming more acceptable and common. The outcomes of treatments for cancers of the oral cavity, pharynx, and larynx, collectively known as head and neck cancer (HNC), vary. Knowing how patients value the outcomes of alternative treatments for HNC may be useful to physicians and healthcare providers in planning treatment interventions and economic (e.g. cost-utility) analyses. Therefore, we conducted a systematic literature review on HNC treatment preferences and utilities. Fifty-six studies were analyzed. Eight of these studies provided quantitative data on utilities elicited by rating scale, time trade-off, or standard gamble methods. Patients reported lower preferences and utilities than physicians and non-patients for outcomes associated with surgery, including radical neck dissection. These findings and the methods used to obtain them are useful to clinicians caring for patients with HNC and in the development of models evaluating interventions to improve HNC outcomes.

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