Should naloxone be prescribed in the ED management of patients with cardiac arrest? A case report and review of literature*

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We report the case of a patient in cardiac arrest with persistent pulseless electrical activity despite optimal treatment, who returned to spontaneous circulation only after the administration of naloxone. It is possible that naloxone may have a role in pulseless electrical activity/asystole related to opioid intoxication and, perhaps, in cardiac arrest related to hypoxia.

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