Current challenges in the evaluation of cardiac safety during drug development: Translational medicine meets the Critical Path Initiative
The Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA•CER) trial: study design and rationale
Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50 trial
The Cholesterol, Hypertension, and Glucose Education (CHANGE) study for African Americans with diabetes: Study design and methodology
Rationale and design of the Rural Andhra Pradesh Cardiovascular Prevention Study (RAPCAPS): A factorial, cluster-randomized trial of 2 practical cardiovascular disease prevention strategies developed for rural Andhra Pradesh, India
Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction
Multicenter randomized study of anticoagulation guided by remote rhythm monitoring in patients with implantable cardioverter-defibrillator and CRT-D devices: Rationale, design, and clinical characteristics of the initially enrolled cohort: The IMPACT study
Systematic review of studies of the effect of hyperoxia on coronary blood flow
Use of β-blockers and effects on heart rate and blood pressure post-acute coronary syndromes: Are we on target?
Detection of myocardial injury in patients with unstable angina using a novel nanoparticle cardiac troponin I assay: Observations from the PROTECT-TIMI 30 Trial
Validation of the Global Registry of Acute Coronary Event (GRACE) risk score for in-hospital mortality in patients with acute coronary syndrome in Canada
ST-elevation myocardial infarction patients can be enrolled in randomized trials before emergent coronary intervention without sacrificing door-to-balloon time
Percutaneous coronary intervention in the Occluded Artery Trial: Procedural success, hazard, and outcomes over 5 years
Effect of prasugrel versus clopidogrel on outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention without stent implantation: A TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitioN with prasugrel (TRITON)-Thrombolysis in Myocardial Infarction (TIMI) 38 Substudy
Association between advanced Killip class at presentation and impaired myocardial perfusion among patients with ST-segment elevation myocardial infarction treated with primary angioplasty and adjunctive glycoprotein IIb-IIIa inhibitors
Biomarker-guided therapy in chronic heart failure: A meta-analysis of randomized controlled trials
The prognostic importance of modifiable risk factors after heart transplantation
The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction
Two-dimensional strain analysis in patients with hypertrophic cardiomyopathy and normal systolic function: A 12-month follow-up study
Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy
Weekend hospital admission and discharge for heart failure: Association with quality of care and clinical outcomes
Heart failure disease management program experience in 4,545 heart failure admissions to a community hospital
Prognosis among survivors of primary ventricular fibrillation in the percutaneous coronary intervention era
Risk factors and comorbidities associated with obesity in children and adolescents after the arterial switch operation and Ross procedure
Current status of cardiac rehabilitation in Latin America and the Caribbean
B-type natriuretic peptide-guided management and outcome in patients with obesity and dyspnea—Results from the BASEL study
Are ejection fraction measurements by echocardiography and left ventriculography equivalent?
Adding socioeconomic status to Framingham scoring might also improve stroke risk evaluation in young adults with hypertension
Response to "Adding socioeconomic status to Framingham scoring might also improve stroke risk evaluation in young adults with hypertension"
Myocardial infarction in saphenous percutaneous intervention: Are we really doing our best?
Response to "Myocardial infarction in saphenous percutaneous intervention: Are we really doing our best?"