Diverse clinical expression of multiple myeloma-atypical presentations

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Eleven of 57 patients with multiple myeloma presented in an atypical fashion. Commonly obtained laboratory tests were examined for a pattern of abnormality that would aid in the diagnosis of these unusual cases. Common to both the usual and unusual modes of presentation were hypercalcemia, hyperglobulinemia, azotemia, and anemia. Knowledge of the possibility of atypical presentations will aid in the early diagnosis of multiple myeloma and result in optimal treatment, lessened morbidity, and increased survival time.

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