Introduction
Glucocorticoid Receptors: ATP and Cell Cycle Dependence, Phosphorylation, and Hormone Resistance
The Glucocorticoid Receptor Protein: A Hormone-dependent Transcription Factor
Molecular Mechanisms of Immunosuppression and Anti-inflammatory Activities by Glucocorticoids
The Epithelium as a Target of Glucocorticoid Action in the Treatment of Asthma
Mechanisms of Action of Glucocorticoids in Asthma
Steroid Receptor Number: Individual Variation and Downregulation by Treatment
Induction of Corticosteroid Resistance In Vitro
Molecular Mechanisms of Clucocorticoid Resistance/Hypersensitivity: Potential Clinical Implications
Corticosteroid-resistant Asthma: Definitions
Mononuclear Cells in Corticosteroid-resistant Asthma
Glucocorticoid-resistant Asthma: T-lymphocyte Defects
Steroid Resistance in Asthma: Molecular Mechanisms
Corticosteroid Resistance in Other Disease States and Tissues
Pathology of Mild, Severe, and Fatal Asthma
Current Management of Asthma Patients with Corticosteroid Resistance
Final Discussion
Conclusions