A randomised controlled trial of intrathecal blockade versus peripheral nerve blockade for day-case knee arthroscopy

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Abstract

Summary

We allocated 100 patients scheduled for day-case knee arthroscopy to unilateral spinal anaesthesia with 40 mg intrathecal hyperbaric prilocaine or to ultrasound-guided femoral-sciatic nerve blockade with 25 ml mepivacaine 2%, 50 participants each. The median (IQR [range]) time to walk was 285 (240–330 [160–515]) min after intrathecal anaesthesia vs 328 (280–362 [150–435]) min after peripheral nerve blockade, p = 0.007. The median (IQR [range]) time to home discharge was 310 (260–350 [160–520]) min after intrathecal anaesthesia vs 335 (290–395 [190–440]) min after peripheral nerve blockade, p = 0.016. There was no difference in time from anaesthetic preparation to readiness for surgery.

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