Preface
Tissue Engineering and Reparative Medicine
In Vitro Systems for Tissue Engineering
The Use of Cells in Reparative Medicine
Reversal of Established Autoimmune Diabetes by in Situ β-Cell Regeneration
Pancreatic Islet Cell Replacement
Building Animals from Stem Cells
Cells for Repair
Genetic Approaches to Craniofacial Tissue Repair
Genetic Approaches to Tissue Repair
Gene Transfer in Tissue Regeneration and Reparative Medicine
Gene-Based Approaches to the Treatment of Hemophilia
Genetic Approaches to the Repair of Connective Tissues
Genetic Approaches to Tissue Repair
Genetic Approaches to Tissue Engineering
Different Osteochondral Potential of Clonal Cell Lines Derived from Adult Human Trabecular Bone
Therapeutic Potential of Implanted Tissue-Engineered Bioartificial Muscles Delivering Recombinant Proteins to the Sheep Heart
Emerging Design Principles in Biomaterials and Scaffolds for Tissue Engineering
Biomaterials and Scaffolds in Reparative Medicine
Hybrid, Composite, and Complex Biomaterials
Biomaterials in Reparative Medicine
Bioscaffolds for Tissue Repair
Manufacturing and Characterization of 3-D Hydroxyapatite Bone Tissue Engineering Scaffolds
Biological Response of Chondrocytes to Hydrogels
Engineering a Biological Joint
The Efficacy of Bone Marrow Stromal Cell-Seeded Knitted PLGA Fiber Scaffold for Achilles Tendon Repair
Effects of Alginate Composition on the Growth and Overall Metabolic Activity of βTC3 Cells
Polymer/Alginate Amalgam for Cartilage- Tissue Engineering
Accelerated and Improved Osteointegration of Implants Biocoated with Bone Morphogenetic Protein 2 (BMP-2)
Molecular Signaling in Bioengineered Tissue Microenvironments
Cell-Cell and Cell-Extracellular Matrix Adhesion Receptors
Convergence of Molecular Signaling and Tissue Engineering
The Role of Extracellular Matrix Heparan Sulfate Glycosaminoglycan in the Activation of Growth Factor Signaling Pathways
Cell Adhesion Molecules Activate Signaling Networks That Influence Proliferation, Gene Expression, and Differentiation
Molecular Signaling
Mechanical Signaling
Molecular Signaling
The Provant® Wound Closure System Induces Activation of p44/42 MAP Kinase in Normal Cultured Human Fibroblasts
p38 MAP Kinase Regulation of AP-2 Binding in TGF-β1-Stimulated Chondrogenesis of Human Trabecular Bone-Derived Cells
TGF-β1-Stimulated Osteoblasts Require Intracellular Calcium Signaling for Enhanced α5 Integrin Expression
Tissue Engineering
Functional Tissue Engineering
Fluorescence Imaging and Engineered Biosensors
Functional Considerations in Tissue-Engineering Whole Organs
Functional Assessment and Tissue Design of Skeletal Muscle
Functional Assessment of Tissues with Magnetic Resonance Imaging
Determination of Responsiveness in Biological Systems Is Dependent on Highly Sensitive Quantitative Measures
Functional Assessment of Engineered Tissues and Elements of Tissue Design
Bioreactors and Bioprocessing for Tissue Engineering
Tissue Engineering as a Subdivision of Bioprocess Engineering
Bioreactors and Bioprocessing
Vascular Assembly in Natural and Engineered Tissues
In Vivo and in Silico Approaches for Analysis and Design of Multisignal, Multicomponent Assembly Processes in Vascular Systems
Vascular Assembly in Engineered and Natural Tissues
Angiogenesis
The Tissue-Engineered Small-Diameter Artery
Vascular Assembly in Engineered and Natural Tissues
Storage and Translational Issues in Reparative Medicine
Neural Tissue Transplantation in Syringomyelia
Stabilization of Tissue-Engineered Products for Transportation and Extended Shelf-Life
Engineering Human Tissues for in Vivo Applications
Cytoprotection by Stabilization of Cell Membranes
Storage and Translational Issues in Reparative Medicine
Development of Artificial Blood Vessels
In Vivo Remodeling of Surgically Constructed Vascular Anastomoses
Simple Method for Increasing Cell-Attachment Ability of Biodegradable Polyester
Engineering of Capillary Patterns in Muscle by a Nonmitogenic Copper-Ribonucleoprotein Angiomorphogen [Angiotropin CuRNP Ribokine],
Noninvasive Monitoring of a Retrievable Bioartificial Pancreas in Vivo
In Vivo Studies to Evaluate Tissue Engineering Techniques
Transition of Stem Cells to Therapeutically Functional Tissue-Specific Cells
In Vivo Remodeling
Regulated in Vivo Remodeling
Consideration of Mechanical Factors
Is in Vivo Remodeling Necessary or Sufficient for Cellular Repair of the Heart?
In Vivo Remodeling
Immunological Concerns with Bioengineering Approaches
Islet Cell Allotransplantation as a Model System for a Bioengineering Approach to Reparative Medicine
Immune Responses to Tissue-Engineered Extracellular Matrix Used as a Bioscaffold
Immunological Barriers (Opportunities?) to the Use of Bioengineered Tissue
An Innate Sense of Danger
Tolerogenic Antigen-Presenting Cells
Chemokines in Neurological Trauma Models
Immune Response to Engineered Tissues and Cells
Tissue Engineering of Meniscal Cartilage Using Perfusion Culture
PROVANT® Wound-Closure System Accelerates Closure of Pressure Wounds in a Randomized, Double-Blind, Placebo-Controlled Trial
Interconnections between Inflammatory and Immune Responses in Tissue Engineering
Modulation of Interferon-Gamma Response by Dermal Fibroblast Extracellular Matrix
Differential Inflammatory and Immunological Responses in Tissue Regeneration and Repair
From Lab Bench to Market
Symposium Summary