Neural Neurotization

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Controlled experimentation using dogs has demonstrated that free nerve-end insertion into a denervated muscle that has lost its motor nerve at the point of entry into that muscle can sprout axons at its implanted end to unite with neuromuscular endplates, either preexisting or new, and result in a functioning muscle. Clinical applications can be found in the treatment of facial paralysis and traumatically induced avulsions of large muscles.

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