Familial Multiple Glomus Tumors: Report of a Pedigree and Literature Review

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Abstract

Glomus tumors are uncommon, benign soft tissue tumors that can occur in a familial or sporadic pattern. Only 15 pedigrees have been reported to date. We report a family with three generations developing multiple glomus tumors of the skin. Although controversy exists over pattern of inheritance, review of the published pedigrees plus this additional one suggests an autosomal dominant inheritance with incomplete penetrance and variable expressivity.

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