Five Year Study of Tissue Reaction to Synthetic Sutures

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Sutures were implanted in the abdominal wall muscles of rabbits and specimens recovered at intervals from six months to five years. Tissue reaction around Nylon and Dacron® was minimal. The reaction to Teflon® coated Dacron was increased because of shedding of the Teflon. The polypropylene sutures showed fragmentation in 4% of the sutures examined and the perisutural formation of bone, cartilage or both in 2.6%.

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