Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism.Design
University medical center.Patients
Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism.Main Outcome Measures
We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes.Results
Mean ± SEM adrenal nodule size was 1.54 ± 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia.Conclusion
Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.